T‑cell LBL (T‑LBL) is a rare lymphoma subtype in adults, and it usually has a dismal prognosis compared to other subtypes of non‑Hodgkin lymphoma. Here, we present a unique case of T‑LBL with myeloproliferative disease. A distinct fusion gene of ZMYM2‑FGFR1 translocation was detected through next‑generation sequencing, and this might be correlated with the translocation of chromosomes 8 and 13 (t[8;13]). Her disease condition seemed to be refractory to multiple lines of chemotherapy. Her lymphoma finally achieved a complete remission after a matched related allogeneic hematopoietic stem cell transplantation.