篇名 | Cutaneous Adverse Drug Reactions in a Tertiary Hospital in Taipei, Taiwan, in 2018 |
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卷期 | 41:4 |
作者 | Yi‑Hsien Chen 、 Tzu‑Ling Hung 、 Hsiang‑Cheng Chen 、 Jui‑Hu Shih 、 Yu‑Ju Chiao 、 Li‑Ching Lin 、 Chih‑Tsung Hung |
頁次 | 161-166 |
關鍵字 | Angioedema 、 cutaneous adverse drug reactions 、 maculopapular eruptions 、 urticaria 、 MEDLINE 、 Scopus |
出刊日期 | 202108 |
DOI | 10.4103/jmedsci.jmedsci_172_19 |
Cutaneous adverse drug reactions (CADRs) are the common adverse reactions ranging from mild self‑limiting skin rash to the life‑threatening severe cutaneous adverse reactions. Aims: The aim of the study was to describe the demographic characteristics of patients, different clinical patterns, and implicated drugs. Methods: This was a retrospective study by analyzing the database established for all ADRs reported from January 1, 2018, to December 31, 2018, in a tertiary care teaching hospital in Taipei, Taiwan. Results: A total of 126 cases of CADRs were reported in 2018. The mean age of patients was 59.06 ± 21.63 years, with a peaking at 60–79‑year‑old (31.7%) and followed by 40–59‑year‑old (25.4%). The male‑to‑female ratio was 1.03:1. The most common skin reaction pattern was maculopapular eruptions (59.5%), followed by angioedema (11.9%), phlebitis (6.3%), and urticaria (6.3%). Most of the CADRs were reported with antibacterials (66.7%), followed by anti‑inflammatory products (11.9%), contrast media (4.8%), and antithrombotic agents (3.2%). Conclusions: We listed the patient characteristics, each pattern of CADRs, and their associated drugs. Such information could help health‑care professionals to assess CADRs and evaluate suspected drugs timely and accurately.