A 48-year-old man with end-stage renal failure on long-term (15 years) hemodialysis presented with a 2-month history of dry cough and exertional dyspnea. High-resolution computed tomography of the chest revealed diffuse ill-defined centrilobular opacities throughout lung parenchyma and ring calcifications in the trachea, main bronchi, and segmental pulmonary arteries of both lungs. Technetium-99m-methylene diphosphonate (Tc-99m MDP) bone scintigraphy demonstrated markedly decreased radioactivity of the skeletal system and increased soft-tissue uptake in both lungs, particular in the right lower zone. These findings were consistent with the features of metastatic pulmonary calcification. Calcified lesions were also seen in the conjunctiva, subcutaneous vessels of upper limbs, and soft tissues of extremities.