Gonococcal keratoconjunctivitis is a well known infection, usually in newborn babies from the developing countries, and it can develop in adults who are latent gonococcal carrier without symptomatic urethritis or endocervicitis. However, the keratoconjunctivitis produced by Neisseria gonorrhoeae is the less frequently reported clinical form of bacterial conjunctivitis. Keratoconjunctivitis of the right eye caused by beta-lactamase-producing Neisseria gonorrhoeae was diagnosed in a 48-yearold woman. Visual acuity of the eye was 6/12 before management. The patient was satisfactorily treated with intravenous ceftriaxone 1000 mg every 12 hours, 5 % topical fortified ceftriaxone every 2 hours, and moxifloxacin eye drops every 2 hours to the right eye. At the week 20 follow-up, her right eye showed healing of the peripheral cornea without vascularization and VA of 6/6.