中國大陸次區域經濟合作戰略對周邊國家與地區的政經影響日趨顯著，本文主要針對中國大陸對其「一國兩制」實施地區的次區域經濟合作的制度與成效進行比較與評估。在「粵港澳合作框架」與「海峽西岸經濟區」的制度比較上，有以許多制度規劃的模仿相似性，在實踐運作上也有明顯的可對照性，加上兩者實施的先後時序，本文將論證「海西區」制度的規劃與實施，具有參照粵港澳整合模式的經驗；此外，在上述兩個次區域經濟合作實施成效評估，實踐主體的差異是「粵港澳」模式優於「海西區」重要因素，也是中國大陸跨邊境次區域經濟合作區實施成功的必要條件。

The impacts of the Mainland China sub-regional economic cooperation strategy to neighboring countries and areas on politics and economy have become more increasingly. This paper specifies the comparisons and estimations of the sub-regional economic cooperation‟s institutions and the effects of the regions where Mainland China implements the principle of “One Country, Two Systems”. In comparison to the institutions of “Guangdong-HongKong-Macau Cooperation Framework” and “Western Taiwan Straits Economic Zone”, there is some resemblance and isomorphism between the schemes of the institutions, the contrast and pattern of the operation is obvious. Furthermore, with the order of the implementation, this paper is going to argue the planning and the implementation of the “Western Taiwan Straits Economic Zone” has the references of the “Guangdong- HongKong-Macau Cooperation Framework”. In addition, in the evaluation of the effectiveness of the foregoing two sub-regional economic cooperation, the differences between the principal parts of the practices are the key factors why “Guangdong-HongKong-Macau Cooperation Framework” surpasses “Western Taiwan Straits Economic Zone”, which is also the requirement of the success of the Mainland China cross-border sub-regional economic cooperation zones.